Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease

- Singanayagam, Aran, Footitt, Joseph, Marczynski, Matthias, Radicioni, Giorgia, Cross, Michael T., Finney, Lydia J., Trujillo-Torralbo, Maria-Belen, Calderazzo, Maria, Zhu, Jie, Aniscenko, Julia, Clarke, Thomas B., Molyneaux, Philip L., Bartlett, Nathan W., Moffatt, Miriam F., Cookson, William O., Wedzicha, Jadwiga, Evans, Christopher M., Boucher, Richard C., Kesimer, Mehmet, Lieleg, Oliver, Mallia, Patrick, Johnston, Sebastian L.

Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon

- Finney, Lydia J., Glanville, Nicholas, Farne, Hugo, Aniscenko, Julia, Fenwick, Peter, Kemp, Samuel V., Trujillo-Torralbo, Maria-Belen, Loo, Su Ling, Calderazzo, Maria Adelaide, Wedzicha, Jadwiga A., Mallia, Patrick, Bartlett, Nathan W., Johnston, Sebastian L., Singanayagam, Aran

Inhaled corticosteroid suppression of cathelicidin drives dysbiosis and bacterial infection in chronic obstructive pulmonary disease

- Singanayagam, Aran, Glanville, Nicholas, Cuthbertson, Leah, Bartlett, Nathan W., Finney, Lydia J., Turek, Elena, Bakhsoliani, Eteri, Calderazzo, Maria Adelaide, Trujillo-Torralbo, Maria-Belen, Footitt, Joseph, James, Phillip L., Fenwick, Peter, Kemp, Samuel V., Clarke, Thomas B., Wedzicha, Jadwiga A., Edwards, Michael R., Moffatt, Miriam, Cookson, William O., Mallia, Patrick, Johnston, Sebastian L.

Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

- Singanayagam, Aran, Glanville, Nicholas, Zhu, Jie, Trujillo-Torralbo, Maria-Belen, Calderazzo, Maria Adelaide, Grainge, Chris, Loo, Su-Ling, Veerati, Punnam Chander, Pathinayake, Prabuddha S., Nichol, Kristy S., Reid, Andrew T., James, Phillip L., Girkin, Jason L., Solari, Roberto, Wark, Peter A. B., Knight, Darryl A., Moffatt, Miriam F., Cookson, William O., Edwards, Michael R., Mallia, Patrick, Bartlett, Nathan W., Johnston, Sebastian L., Ching, Yee Man, Marcellini, Andrea, Porter, James D., Toussaint, Marie, Walton, Ross P., Finney, Lydia J., Aniscenko, Julia

The MIF antagonist ISO-1 attenuates corticosteroid-insensitive inflammation and airways hyperresponsiveness in an ozone-induced model of COPD

- Russell, Kirsty E., Chung, Kian Fan, Starkey, Malcolm R., Hansbro, Philip M., Adcock, Ian M., Wiegman, Coen H., Clarke, Colin J., Durham, Andrew L., Mallia, Patrick, Footit, Joseph, Johnston, Sebastian L., Barnes, Peter J., Hall, Simon R., Simpson, Karen D.